Racial Disparities Associated with Non-Infectious Anterior Uveitis and Concurrent Ocular Conditions: Results from a Large Multi-Institutional Research Network

Authors

• Enny Oyeniran, NJEye and Ear, Englewood, New Jersey, USA.
• Abhisri Ramesh, Department of Ophthalmology, The George Washington University School of Medicine and Health Sciences, Washington, District of Columbia, USA.
• Rahul Raiker, West Virginia University School of Medicine, Morgantown, West Virginia, USA.
• Haig Pakhchanian, Department of Ophthalmology, The George Washington University School of Medicine and Health Sciences, Washington, District of Columbia, USA.
• Daniel Akinbolue, Department of Ophthalmology, The George Washington University School of Medicine and Health Sciences, Washington, District of Columbia, USA.
• Cecilia S. Lee, Department of Ophthalmology, University of Washington, Seattle, Washington, USA.
• Emily Y. Chew, National Eye Institute, National Institutes of Health, Bethesda, Maryland, USA.
• Angela Elam, Kellogg Eye Center, University of Michigan, Ann Arbor, Michigan, USA.
• H Nida Sen, Department of Ophthalmology, The George Washington University School of Medicine and Health Sciences, Washington, District of Columbia, USA.
• Sunil Bellur, National Eye Institute, National Institutes of Health, Bethesda, Maryland, USA.
• Shilpa Kodati, Kellogg Eye Center, University of Michigan, Ann Arbor, Michigan, USA.

Document Type

Journal Article

Publication Date

3-12-2026

Journal

Ocular immunology and inflammation

DOI

10.1080/09273948.2026.2637781

Keywords

Disparities; glaucoma; ocular conditions; race; uveitis

Abstract

PURPOSE: To examine the differences between non-Hispanic White patients and other racial/ethnic groups and their likelihood of concurrent diagnosis with non-infectious anterior uveitis (AU) and other ocular conditions. METHODS: The TriNetX database was used to identify adult patients with an incident diagnosis of non-infectious AU using ICD-10 codes. Non-Hispanic White patients with AU were compared to three groups (non-White, Black, and Hispanic patients). Odds ratios and 95% CIs for ocular conditions at the time of diagnosis with AU were compared between cohorts to evaluate the likelihood of a concurrent diagnosis with another ocular condition. RESULTS: In the first group, Non-Hispanic White patients had greater odds of legal blindness (OR: 1.994; 95% CI: 1.5882.503) and epiretinal membrane (OR: 1.794; 95% CI: 1.514-2.126) compared to non-White patients. In the second group, Non-Hispanic White patients had lower odds of glaucoma (OR: 0.853; 95% CI: 0.805-0.904), glaucoma suspect (OR: 0.797; 95% CI: 0.735-0.864), and open angle glaucoma (OR: 0.53; 95% CI: 0.460-0.611) compared to Black patients. In the third group, Non-Hispanic White patients had lower odds of cataracts (OR: 0.755; 95% CI: 0.604-0.945), glaucoma (OR:0.706; 95% CI: 0.574-0.868), and glaucoma suspect (OR: 0.743; 95% CI: 0.557 -0.991) compared to Hispanic patients. CONCLUSION: Non-Hispanic White patients diagnosed with AU had higher odds of legal blindness, and epiretinal membrane compared to non-White patients. Black and Hispanic patients were more likely to have glaucoma-related conditions at the time of AU diagnosis.

APA Citation

Oyeniran, Enny; Ramesh, Abhisri; Raiker, Rahul; Pakhchanian, Haig; Akinbolue, Daniel; Lee, Cecilia S.; Chew, Emily Y.; Elam, Angela; Sen, H Nida; Bellur, Sunil; and Kodati, Shilpa, "Racial Disparities Associated with Non-Infectious Anterior Uveitis and Concurrent Ocular Conditions: Results from a Large Multi-Institutional Research Network" (2026). GW Authored Works. Paper 8890.
https://hsrc.himmelfarb.gwu.edu/gwhpubs/8890

Department

Ophthalmology