Interhemispheric-Transcortical Approach for Resection of an Atypical Teratoid/Rhabdoid Tumor (AT/RT) of the Left Lateral and Third Ventricle

Authors

Douglas Chung, Department of Neurological Surgery, George Washington University, Washington, District of Columbia, United States.
Patrick F. O' Brien, Department of Neurological Surgery, Children's National Medical Center, Washington, District of Columbia, United States.
Hasan Syed, Department of Neurological Surgery, Children's National Medical Center, Washington, District of Columbia, United States.

Document Type

Journal Article

Publication Date

7-1-2025

Journal

Journal of neurological surgery reports

Volume

86

Issue

3

DOI

10.1055/a-2701-4192

Keywords

AT/RT; atypical teratoid/rhabdoid tumor; high-grade glioma; pediatric neuro-oncology; ventricular surgery

Abstract

INTRODUCTION: Atypical teratoid/rhabdoid tumors (AT/RT) are malignant central nervous system (CNS) tumors that represent 3% of all pediatric CNS tumors. Majority of cases have SMARCB1 gene mutations and historically carried a poor prognosis. CASE PRESENTATION: A 9-year-old boy was diagnosed with a third ventricle AT/RT and initially underwent endoscopic surgical biopsy. Subsequent tumor resection was completed using an interhemispheric-transcortical approach. LESSONS: Surgical approaches to ventricular system must be tailored to the tumor characteristics on a case-by-case basis. We present a case using a transcortical approach for understanding of the microsurgical anatomy for safe resection of a third ventricle AT/RT.

APA Citation

Chung, Douglas; O' Brien, Patrick F.; and Syed, Hasan, "Interhemispheric-Transcortical Approach for Resection of an Atypical Teratoid/Rhabdoid Tumor (AT/RT) of the Left Lateral and Third Ventricle" (2025). GW Authored Works. Paper 7872.
https://hsrc.himmelfarb.gwu.edu/gwhpubs/7872

Department

School of Medicine and Health Sciences Resident Works