Large Basal Cell Carcinoma Treated with Combination Topical Therapy

Authors

Kabir Al-Tariq, Mr. Al-Tariq is with the Georgetown University School of Medicine in Washington, District of Columbia.
Rama Abdin, Ms. Abdin is with the Charles E. Schmidt College of Medicine at Florida Atlantic University in Boca Raton, Florida.
Naiem T. Issa, Dr. Issa is with Forefront Dermatology in Vienna, Virginia, Issa Research and Consulting, LLC, in Springfield, Virginia, the Dr. Phillip Frost Department of Dermatology at the University of Miami Miller School of Medicine in Miami, Florida, and the George Washington University School of Medicine and Health Sciences in Washington, District of Columbia.

Document Type

Journal Article

Publication Date

8-1-2025

Journal

The Journal of clinical and aesthetic dermatology

Volume

18

Issue

8

Keywords

Nodular basal cell carcinoma; combination topical therapy

Abstract

Basal cell carcinoma (BCC) is the most common skin cancer in the United States. Common treatment approaches for superficial, small, and/or low grade BCCs include topical therapy or curettage plus electrodesiccation and cryotherapy. For larger, high-grade, and/or certain subtypes of BCC, surgical therapy is typically pursued, occasionally under anesthesia for large lesions. While surgical therapy provides good clearance rates, it is not feasible for all patients. Therefore, it is important for physicians to understand alternative, less invasive approaches to treating BCC in order to provide patients with the best possible evidence-based care. In this case, we describe a combination topical treatment approach for a large nodular BCC in an elderly patient in a tough to excise inguinal region.

APA Citation

Al-Tariq, Kabir; Abdin, Rama; and Issa, Naiem T., "Large Basal Cell Carcinoma Treated with Combination Topical Therapy" (2025). GW Authored Works. Paper 7835.
https://hsrc.himmelfarb.gwu.edu/gwhpubs/7835

Department

Dermatology