Hypertension and COVID-19: Updates from the era of vaccines and variants

Document Type

Journal Article

Publication Date

3-1-2022

Journal

Journal of clinical & translational endocrinology

Volume

27

DOI

10.1016/j.jcte.2021.100285

Keywords

ACE inhibitors; Alpha blockers; Angiotensin receptor blockers; Beta blockers; COVID-19; Calcium channel blockers; Catecholamines; Delta variant; Hypertension; SARS-CoV-2; Vaccines

Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the pathogen responsible for coronavirus disease 2019 (COVID-19) has been a major cause of morbidity and mortality globally. Older age, and the presence of certain components of metabolic syndrome, including hypertension have been associated with increased risk for severe disease and death in COVID-19 patients. The role of antihypertensive agents in the pathogenesis of COVID-19 has been extensively studied since the onset of the pandemic. This review discusses the potential pathophysiologic interactions between hypertension and COVID-19 and provides an up-to-date information on the implications of newly emerging SARS-CoV-2 variants, and vaccines on patients with hypertension.

Department

Medicine

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