Congress of neurological surgeons systematic review and evidence-based guidelines update on the role of cytoreductive surgery in the management of progressive glioblastoma in adults

Authors

Hayes H. Patrick, Department of Neurological Surgery, George Washington University, 900 23rd St NW, Washington, DC, 20037, USA. hpatrick@gwu.edu.
Jonathan H. Sherman, Department of Neurosurgery, West Virginia University Rockefeller Neuroscience Institute, Martinsburg, WV, USA.
J Bradley Elder, Department of Neurosurgical Oncology, The Ohio State University, Wexner Medical Center, Columbus, OH, USA.
Jeffrey J. Olson, Department of Neurosurgery, Emory University School of Medicine, Atlanta, GA, USA.

Document Type

Journal Article

Publication Date

3-4-2022

Journal

Journal of neuro-oncology

DOI

10.1007/s11060-021-03881-w

Keywords

Cytoreductive surgery; Glioblastoma; Recurrent

Abstract

QUESTION: In patients with previously diagnosed glioblastoma who are suspected of experiencing progression, does repeat cytoreductive surgery improve progression free survival or overall survival compared to alternative interventions? TARGET POPULATION: These recommendations apply to adults with previously diagnosed glioblastoma who are suspected of experiencing progression of the neoplastic process and are amenable to surgical resection. RECOMMENDATION: Level II: Repeat cytoreductive surgery is recommended in progressive glioblastoma patients to improve overall survival.

APA Citation

Patrick, Hayes H.; Sherman, Jonathan H.; Elder, J Bradley; and Olson, Jeffrey J., "Congress of neurological surgeons systematic review and evidence-based guidelines update on the role of cytoreductive surgery in the management of progressive glioblastoma in adults" (2022). GW Authored Works. Paper 633.
https://hsrc.himmelfarb.gwu.edu/gwhpubs/633

Department

Neurological Surgery