Peri- and postoperative outcomes in patients with endometriosis undergoing hysterectomy

Authors

Malin Brunes, Department of Clinical Science and Education, Södersjukhuset, Karolinska Institutet, Sweden; Division of Obstetrics and Gynecology at Södersjukhuset, Stockholm, Sweden. Electronic address: malin.brunes@regionstockholm.se.
Ulrika Johannesson, Department of Clinical Sciences, Danderyd Hospital, Karolinska Institutet, Sweden; Division of Obstetrics and Gynecology at Danderyd Hospital, Stockholm, Sweden. Electronic address: ulrika.johannesson@regionstockholm.se.
Henrike Häbel, Institute for Environmental Medicine, Karolinska Institutet, Stockholm, Sweden. Electronic address: henrike.habel@ki.se.
Catharina Forsgren, Department of Clinical Sciences, Danderyd Hospital, Karolinska Institutet, Sweden; Division of Obstetrics and Gynecology at Danderyd Hospital, Stockholm, Sweden. Electronic address: catharina.forsgren@regionstockholm.se.
Gaby Moawad, Department of Obstetrics and Gynecology, George Washington University, Washington, DC, USA.
Marion Ek, Department of Clinical Science and Education, Södersjukhuset, Karolinska Institutet, Sweden; Division of Obstetrics and Gynecology at Södersjukhuset, Stockholm, Sweden. Electronic address: marion.ek@regionstockholm.se.

Document Type

Journal Article

Publication Date

3-9-2022

Journal

European journal of obstetrics, gynecology, and reproductive biology

Volume

272

DOI

10.1016/j.ejogrb.2022.02.180

Keywords

Complication; Conversion; Endometriosis; Hysterectomy; Robotic

Abstract

OBJECTIVES: To assess whether hysterectomy in patients with endometriosis is associated with higher proportion of complications compared with patients without, and whether route of hysterectomy affects this outcome. STUDY DESIGN: This is a population-based retrospective cohort study. Data were prospectively obtained from three National Swedish Registers. Patients undergoing a benign hysterectomy between 2015 and 2017 in Sweden were included in the study and were grouped according to a histology-proven diagnosis of endometriosis. Different hysterectomy modes were compared in patients with endometriosis. Perioperative data and postoperative complications up to 1 year after surgery were collected and measured. RESULTS: In all, 8,747 patients underwent a benign hysterectomy, and 1,166 patients with endometriosis was compared with 7,581 patients without. Patients with endometriosis had higher proportion of complications (adjusted Odds ratio aOR 1.2, 95% CI 1.0-1.4), were more often converted to abdominal hysterectomy (aOR 1.7, 95% CI 1.1-2.6), had higher estimated blood loss (EBL) (200-500 ml; aOR 1.8, 95% CI 1.4-2.3, >500 ml; aOR 3.1, 95% CI 2.2-4.4) and a longer operative time (1-2 h; aOR 2.1, 95% CI 1.4-3.2, >2 h; aOR 4.3, 95% CI 2.7-6.6) than endometriosis-free patients. The conversion rate was 13.8 times higher in total laparoscopic hysterectomy (TLH) compared with robotic-assisted laparoscopic hysterectomy (RATLH) (aOR 13.8, 95% CI 3.6-52.4). CONCLUSION: Higher conversion rate, higher EBL and higher frequency of complications were seen in patients with endometriosis. RATLH was associated with lower conversion rate compared to TLH.

APA Citation

Brunes, Malin; Johannesson, Ulrika; Häbel, Henrike; Forsgren, Catharina; Moawad, Gaby; and Ek, Marion, "Peri- and postoperative outcomes in patients with endometriosis undergoing hysterectomy" (2022). GW Authored Works. Paper 612.
https://hsrc.himmelfarb.gwu.edu/gwhpubs/612

Department

Obstetrics and Gynecology