Healthy Drinks, Healthy Teeth - Ciunerkaq Tanqigtuq (The Future is Bright): A study protocol for a community-based, non-randomized sociobehavioral trial to reduce added sugar intake in Alaska Native Yup'ik children in the Yukon-Kuskokwim Delta

Donald L. Chi, Department of Oral Health Sciences, University of Washington School of Dentistry, 1959 NE Pacific Street, Box 357475, Seattle, WA 98195, USA; Department of Health Systems and Population Health, University of Washington School of Public Health, 3980 15th Ave NE, Fourth Floor, Box 351621, Seattle, WA 98195, USA. Electronic address: dchi@uw.edu.
Frances Marcus Lewis, Department of Child, Family and Population Health Nursing, University of Washington School of Nursing, Health Sciences Building, Room T-301, 1959 NE Pacific Street, Seattle, WA, 98195, USA.
Philip Weinstein, Department of Oral Health Sciences, University of Washington School of Dentistry, 1959 NE Pacific Street, Box 357475, Seattle, WA 98195, USA.
Lloyd Mancl, Department of Oral Health Sciences, University of Washington School of Dentistry, 1959 NE Pacific Street, Box 357475, Seattle, WA 98195, USA.
Peter Milgrom, Department of Oral Health Sciences, University of Washington School of Dentistry, 1959 NE Pacific Street, Box 357475, Seattle, WA 98195, USA.
Todd Edwards, Department of Health Systems and Population Health, University of Washington School of Public Health, 3980 15th Ave NE, Fourth Floor, Box 351621, Seattle, WA 98195, USA.
Susan Coldwell, Department of Oral Health Sciences, University of Washington School of Dentistry, 1959 NE Pacific Street, Box 357475, Seattle, WA 98195, USA.
Diane O'Brien, Center for Alaska Native Health Research, Institute of Arctic Biology, University of Alaska Fairbanks, 2141 Koyukuk Dr, Fairbanks, AK 99775, USA.
Andrea Bersamin, Center for Alaska Native Health Research, Institute of Arctic Biology, University of Alaska Fairbanks, 2141 Koyukuk Dr, Fairbanks, AK 99775, USA.
Scarlett Hopkins, Department of Obstetrics and Gynecology, Oregon Health & Science University, 3181 SW Sam Jackson Park Road, Portland, OR 97239, USA.
Eliza Orr, Department of Oral Health Sciences, University of Washington School of Dentistry, 1959 NE Pacific Street, Box 357475, Seattle, WA 98195, USA.
Patricia Rivera, Center for Alaska Native Health Research, Institute of Arctic Biology, University of Alaska Fairbanks, 2141 Koyukuk Dr, Fairbanks, AK 99775, USA.
Dane Lenaker, Southeast Alaska Regional Health Consortium, Department of Dentistry, 3245 Hospital Drive, Juneau, AK 99801, USA.
Allison Sylvetsky, Department of Exercise and Nutrition Sciences, Milken Institute School of Public Health, The George Washington University, 950 New Hampshire Ave NW, Washington, DC 20052,USA.
Joel Gittelsohn, Department of International Health, Johns Hopkins Bloomberg School of Public Health, 615 N. Wolfe Street, Baltimore, MD 21205, USA.
Peter Walter, Clinical Mass Spectrometry Core, NIH/NIDDK, Building 10-9C106, 10 Center Drive, MSC-1805, Bethesda, MD 20892, USA.
Cameron L. Randall, Department of Oral Health Sciences, University of Washington School of Dentistry, 1959 NE Pacific Street, Box 357475, Seattle, WA 98195, USA.
Deanna Wiseman, Department of Oral Health Sciences, University of Washington School of Dentistry, 1959 NE Pacific Street, Box 357475, Seattle, WA 98195, USA.
Andrea Dock, Department of Oral Health Sciences, University of Washington School of Dentistry, 1959 NE Pacific Street, Box 357475, Seattle, WA 98195, USA.
Alice Ko, Department of Oral Health Sciences, University of Washington School of Dentistry, 1959 NE Pacific Street, Box 357475, Seattle, WA 98195, USA.
Joshua Orack, Department of Oral Health Sciences, University of Washington School of Dentistry, 1959 NE Pacific Street, Box 357475, Seattle, WA 98195, USA.
Deeksha Nemawarkar, Department of Oral Health Sciences, University of Washington School of Dentistry, 1959 NE Pacific Street, Box 357475, Seattle, WA 98195, USA.
Shraddha Panchal, Department of Oral Health Sciences, University of Washington School of Dentistry, 1959 NE Pacific Street, Box 357475, Seattle, WA 98195, USA.
Jane Soper, Department of Oral Health Sciences, University of Washington School of Dentistry, 1959 NE Pacific Street, Box 357475, Seattle, WA 98195, USA.
Courtney M. Hill, Department of Oral Health Sciences, University of Washington School of Dentistry, 1959 NE Pacific Street, Box 357475, Seattle, WA 98195, USA.
Darragh Kerr, Department of Oral Health Sciences, University of Washington School of Dentistry, 1959 NE Pacific Street, Box 357475, Seattle, WA 98195, USA.
Daisy Patiño Nguyen, Department of Oral Health Sciences, University of Washington School of Dentistry, 1959 NE Pacific Street, Box 357475, Seattle, WA 98195, USA.
Chien-Yu Chen, Department of Oral Health Sciences, University of Washington School of Dentistry, 1959 NE Pacific Street, Box 357475, Seattle, WA 98195, USA.
Ellen MacLachlan, Department of Oral Health Sciences, University of Washington School of Dentistry, 1959 NE Pacific Street, Box 357475, Seattle, WA 98195, USA.

Document Type

Journal Article

Publication Date

11-1-2024

Journal

Contemporary clinical trials

Volume

147

DOI

10.1016/j.cct.2024.107734

Keywords

Added sugar; Artificial sweeteners; Health inequities; Indigenous populations; Oral health behaviors; Oral health disparities; Sugar-sweetened beverages

Abstract

BACKGROUND: This study protocol describes a community-based intervention that will seek to reduce added sugar intake in Yup'ik Alaska Native children by targeting reductions in sugar-sweetened fruit drinks. METHODS: A two-group non-randomized design will be used to evaluate the intervention in three Yup'ik communities in Alaska focusing on children age 1 to less than age 12 years with a minimum enrollment target of 192 children. Families in the intervention arm will participate in a program consisting of five sessions plus four brief check-ins, all delivered by a Yup'ik Community Health Worker. Modifications to the local store environment will be made to give families a place to purchase sugar-free water enhancers. Families in the delayed treatment control arm will receive no intervention during the main study period. There will be five data collection visits (baseline, 1-month, 3-months, 6-months, and 12-months) that will include collection of survey and dietary data, and a hair and plaque sample from each participating child. The outcomes will be change, from baseline to 6 months, in added sugar intake based on a validated hair biomarker (grams of added sugar/day). We hypothesize children in the intervention arm will have greater reductions in added sugar intake compared to children in the control arm as measured by the hair biomarker. DISCUSSION: This is one of the first known community-based sociobehavioral interventions aimed specifically at reducing added sugar intake in Alaska Native communities by targeting sugar-sweetened fruit drinks. TRIAL REGISTRATION: ClinicalTrials.govNCT05219448 (first posted on February 2, 2022).

Department

Exercise and Nutrition Sciences

Link to Full Text

Share

COinS