Effect of a Dietary Intervention on Insulin Requirements and Glycemic Control in Type 1 Diabetes: A 12-Week Randomized Clinical Trial

Authors

Hana Kahleova, Physicians Committee for Responsible Medicine, Washington, DC.
Tatiana Znayenko-Miller, Physicians Committee for Responsible Medicine, Washington, DC.
Karen Smith, Physicians Committee for Responsible Medicine, Washington, DC.
Cyrus Khambatta, Mastering Diabetes, Santa Monica, CA.
Robby Barbaro, Mastering Diabetes, Santa Monica, CA.
Macy Sutton, Physicians Committee for Responsible Medicine, Washington, DC.
Danielle N. Holtz, Physicians Committee for Responsible Medicine, Washington, DC.
Mark Sklar, Private Practice, Endocrinology, Diabetes & Metabolism, Washington, DC.
Desiree Pineda, Private Practice, Internal Medicine and Endocrinology, Washington, DC.
Richard Holubkov, School of Medicine, University of Utah, Salt Lake City, UT.
Neal D. Barnard, Physicians Committee for Responsible Medicine, Washington, DC.

Document Type

Journal Article

Publication Date

1-1-2024

Journal

Clinical diabetes : a publication of the American Diabetes Association

Volume

42

Issue

3

DOI

10.2337/cd23-0086

Abstract

This study compared the effects of a low-fat vegan diet to those of a portion-controlled diet in people with type 1 diabetes. Over 12 weeks, the average total daily dose of insulin decreased significantly and insulin sensitivity increased significantly in the vegan group, while no significant changes were observed in the group receiving the portion-controlled diet. Total and LDL cholesterol decreased in the vegan group, as did the ratio of blood urea nitrogen to creatinine. A1C decreased in both groups. These findings suggest that a low-fat vegan diet may yield improvements in insulin sensitivity, insulin requirements, glycemic control, and markers of cardiovascular and renal health compared with a portion-controlled diet in people with type 1 diabetes.

APA Citation

Kahleova, Hana; Znayenko-Miller, Tatiana; Smith, Karen; Khambatta, Cyrus; Barbaro, Robby; Sutton, Macy; Holtz, Danielle N.; Sklar, Mark; Pineda, Desiree; Holubkov, Richard; and Barnard, Neal D., "Effect of a Dietary Intervention on Insulin Requirements and Glycemic Control in Type 1 Diabetes: A 12-Week Randomized Clinical Trial" (2024). GW Authored Works. Paper 5342.
https://hsrc.himmelfarb.gwu.edu/gwhpubs/5342

Department

Medicine