3D-Bioprinted Skin Tissues for Improving Wound Healing: Current Status and Perspective

Authors

Nikita Gopakumar, Department of Mechanical Engineering, University of Nevada, Las Vegas, Las Vegas, USA.
Abdulla M. Ali, Department of Medicine, George Washington University School of Medicine and Health Sciences, Washington, DC, USA.
Sumayah Oudda, Department of Biology, Johns Hopkins University, Baltimore, MD, USA.
Amarnath Singam, Department of Mechanical Engineering, University of Nevada, Las Vegas, Las Vegas, USA.
Seungman Park, Department of Mechanical Engineering, University of Nevada, Las Vegas, Las Vegas, USA. seungman.park@unlv.edu.

Document Type

Journal Article

Publication Date

7-10-2024

Journal

Advances in experimental medicine and biology

DOI

10.1007/5584_2024_817

Keywords

Bioprinting; Dermis; Epidermis; Hypodermis; Skin tissue; Wound healing

Abstract

Advancements in tissue engineering enable the fabrication of complex and functional tissues or organs. In particular, bioprinting enables controlled and accurate deposition of cells, biomaterials, and growth factors to create complex 3D skin constructs specific to a particular individual. Despite these advancements, challenges such as vascularization, long-term stability, and regulatory considerations hinder the clinical translation of bioprinted skin constructs. This chapter focuses on such approaches using advanced biomaterials and bioprinting techniques to overcome the current barriers in wound-healing studies. Moreover, it addresses current obstacles in wound-healing studies, highlighting the need for continued research and innovation to overcome these barriers and facilitate the practical utilization of bioprinted skin constructs in clinical settings.

APA Citation

Gopakumar, Nikita; Ali, Abdulla M.; Oudda, Sumayah; Singam, Amarnath; and Park, Seungman, "3D-Bioprinted Skin Tissues for Improving Wound Healing: Current Status and Perspective" (2024). GW Authored Works. Paper 5302.
https://hsrc.himmelfarb.gwu.edu/gwhpubs/5302

Department

School of Medicine and Health Sciences Student Works