Pediatric lymphoproliferative disorders associated with inborn errors of immunity
Authors
Jinjun Cheng, Department of Pathology and Laboratory Medicine, Children's National Hospital, Washington, DC, United States of America; Centers for Cancer & Blood Disorders and Cancer & Immunology Research, Children's National Hospital, Washington, DC, United States of America; The George Washington University School of Medicine and Health Sciences, Washington, DC, United States of America. Electronic address: jcheng2@childrensnational.org.
Blachy J. Dávila Saldaña, Centers for Cancer & Blood Disorders and Cancer & Immunology Research, Children's National Hospital, Washington, DC, United States of America; The George Washington University School of Medicine and Health Sciences, Washington, DC, United States of America.
Shanmuganathan Chandrakasan, Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Atlanta, GA, United States of America.
Michael Keller, Centers for Cancer & Blood Disorders and Cancer & Immunology Research, Children's National Hospital, Washington, DC, United States of America; The George Washington University School of Medicine and Health Sciences, Washington, DC, United States of America.
Document Type
Journal Article
Publication Date
7-26-2024
Journal
Clinical immunology (Orlando, Fla.)
DOI
10.1016/j.clim.2024.110332
Keywords
EBV; Inborn errors of immunity; International consensus classification; Lymphoma; Lymphoproliferative disorder; WHO classification
Abstract
Both non-malignant and malignant lymphoproliferative disorders (LPD) are commonly seen in patients with inborn errors of immunity (IEI), which may be the presenting manifestations or may develop during the IEI disease course. Here we review the clinical, histopathological, and molecular features of benign and malignant LPD associated with IEI and recognize the diagnostic challenges.
APA Citation
Cheng, Jinjun; Dávila Saldaña, Blachy J.; Chandrakasan, Shanmuganathan; and Keller, Michael, "Pediatric lymphoproliferative disorders associated with inborn errors of immunity" (2024). GW Authored Works. Paper 5224.
https://hsrc.himmelfarb.gwu.edu/gwhpubs/5224
