Distal Ileitis Caused by Diffuse Large B-Cell Lymphoma in an Elderly Patient From Honduras

Document Type

Journal Article

Publication Date

6-1-2024

Journal

ACG case reports journal

Volume

11

Issue

6

DOI

10.14309/crj.0000000000001356

Keywords

Colonoscopy; Crohn's Disease; Diffuse Large B-Cell Lymphoma; Gastrointestinal Lymphoma; Stricture

Abstract

Primary gastrointestinal non-Hodgkin lymphoma, while rare, most often presents as diffuse large B-cell lymphoma located in the stomach or ileocecal region. Presenting symptoms include abdominal pain, gastrointestinal bleeding, weight loss, or obstructive symptoms. Imaging can reveal ileitis or obstruction. We report a case of a man from Honduras with latent tuberculosis and chronic hepatitis B who presented with features of Crohn's disease through clinical, radiologic, and endoscopic findings but was ultimately diagnosed with diffuse large B-cell lymphoma by histology. We emphasize the importance of maintaining a broad differential for ileitis and the importance of histologic sampling when evaluating ileitis.

Department

Medicine

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