Antibiotic adherence in dermatologic surgery: a Multicenter prospective cohort study

Authors

Surya A. Veerabagu, Department of Dermatology, University of New Mexico, Albuquerque, NM, USA. suryaveerabagu@gmail.com.
Leora Aizman, Department of Dermatology, Johns Hopkins University, Baltimore, MD, USA.
Brian Cheng, Department of Medicine, Indiana University, Vincennes, IN, USA.
Michael P. Lee, Department of Dermatology, Loma Linda University, Loma Linda, CA, USA.
John S. Barbieri, Department of Dermatology, Brigham and Women's Hospital, Boston, MA, USA.
Nicholas Golda, Department of Dermatology, University of Missouri, Columbia, MO, USA.
Alexis E. Carrington, Department of Dermatology, George Washington University School of Medicine and Health Sciences, Washington, DC, USA.
Allison Weinkle Mitevski, Department of Dermatology, University of California - Davis, Davis, CA, USA.
Peter Bittar, Department of Dermatology, Indiana University School of Medicine, Indianapolis, IN, USA.
David R. Carr, Division of Dermatology, The Ohio State University, Columbus, OH, USA.
Daniel B. Eisen, Department of Dermatology, University of California - Davis, Davis, CA, USA.
Ally-Khan Somani, Department of Dermatology, Indiana University School of Medicine, Indianapolis, IN, USA.
Christopher J. Miller, Department of Dermatology, Hospital of the University of Pennsylvania, Philadelphia, PA, USA.
Joseph F. Sobanko, Department of Dermatology, Hospital of the University of Pennsylvania, Philadelphia, PA, USA.
Thuzar M. Shin, Department of Dermatology, Hospital of the University of Pennsylvania, Philadelphia, PA, USA.
H William Higgins Ii, Department of Dermatology, Hospital of the University of Pennsylvania, Philadelphia, PA, USA.
Cerrene N. Giordano, Department of Dermatology, Hospital of the University of Pennsylvania, Philadelphia, PA, USA.
Jeremy R. Etzkorn, Department of Dermatology, Hospital of the University of Pennsylvania, Philadelphia, PA, USA.

Document Type

Journal Article

Publication Date

5-17-2024

Journal

Archives of dermatological research

Volume

316

Issue

5

DOI

10.1007/s00403-024-02912-6

Keywords

Antibiotic adherence; Antibiotic compliance; Antibiotics; Dermatologic surgery

Abstract

Understanding patient non-adherence to prescribed antibiotics can inform clinical practices, patient counseling, and antibiotic efficacy study design in dermatology. The primary objective was to determine the rate of and reasons for antibiotic non-adherence in the dermatologic surgery setting. The secondary objective was to test the applicability of previously studied survey questions for antibiotic non-adherence screening in the dermatologic surgery setting. Five academic outpatient dermatologic surgery centers across the United States conducted one multicenter prospective cohort study. Dermatologic surgery patients ≥ 18 years of age who were prescribed an antibiotic were included as part of this study. 15.2% (42/276) of patients did not adhere to their antibiotic regimen after dermatologic surgery. Most common reasons for incomplete antibiotic courses included forgotten antibiotics (42.9%,18/42) and side effects (28.6%, 12/42). Previously evaluated questions to identify and predict non-adherence had modest performance in the dermatologic surgery setting (Area under the curve of 0.669 [95% CI (0.583-0.754)]). Antibiotic non-adherence after skin surgery is prevalent and commonly due to reasons that physicians can address with patients.

APA Citation

Veerabagu, Surya A.; Aizman, Leora; Cheng, Brian; Lee, Michael P.; Barbieri, John S.; Golda, Nicholas; Carrington, Alexis E.; Mitevski, Allison Weinkle; Bittar, Peter; Carr, David R.; Eisen, Daniel B.; Somani, Ally-Khan; Miller, Christopher J.; Sobanko, Joseph F.; Shin, Thuzar M.; Higgins Ii, H William; Giordano, Cerrene N.; and Etzkorn, Jeremy R., "Antibiotic adherence in dermatologic surgery: a Multicenter prospective cohort study" (2024). GW Authored Works. Paper 4917.
https://hsrc.himmelfarb.gwu.edu/gwhpubs/4917

Department

School of Medicine and Health Sciences Resident Works