Lack of association of atopic dermatitis severity and morphology with asthma onset and control

Document Type

Journal Article

Publication Date

5-25-2024

Journal

Archives of dermatological research

Volume

316

Issue

6

DOI

10.1007/s00403-024-03013-0

Keywords

Asthma; Atopic dermatitis; Atopy; Comorbidity; Eczema; Severity

Abstract

BACKGROUND: Asthma is one of the most well-recognized comorbidities of atopic dermatitis (AD). However, the relationship of AD severity and morphology with asthma characteristics in adults is not well defined. OBJECTIVES: To understand associations of AD severity and morphology with comorbid asthma age-of-onset and control in adults with AD. METHODS: A cross-sectional, dermatology practice-based study was performed in adults (≥ 18 years) with AD and history of asthma (N = 252). Self-administered electronic questionnaires were completed by patients, including demographics, patient-reported outcomes measures of AD severity, history of asthma, age-of-onset, and Asthma Control Test (ACT). Multivariable logistic regression models were constructed to examine relationships between AD severity and morphology with asthma age-of-onset and control. RESULTS: The mean ± standard deviation ACT score was 21.7 ± 4.3 (range 5-25), with 55 (21.8%) having ACT scores ≤ 19 indicating poorly controlled asthma. AD severity and morphology were not associated with adult-onset asthma or poor asthma control. CONCLUSIONS: AD severity and morphology were not consistently associated with comorbid asthma age-of-onset or control in adults with AD.

Department

Dermatology

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