Epilepsy in Africa: a multifaceted perspective on diagnosis, treatment, and community support
Document Type
Journal Article
Publication Date
1-1-2024
Journal
Annals of medicine and surgery (2012)
Volume
86
Issue
1
DOI
10.1097/MS9.0000000000001536
Keywords
africa; epilepsy; epilepsy treatment; low- and middle-income countries; stigma; treatment development
Abstract
Epilepsy is the most widespread neurological disorder in Africa, affecting an estimated 25 million people. The disorder is characterized by recurrent seizures, which can be caused by a variety of factors, including past trauma, central nervous system infections, and genetic disorders. Diagnosis and treatment of epilepsy are challenging in African patients due to several factors, including the low socioeconomic status of the residents and limited access to appropriate medication. Phenobarbital remains the only drug widely available to patients, but it is not always effective and can have significant side effects. In addition to the medical challenges, individuals with epilepsy also face a lot of social stigmas in Africa. Widespread superstitions and false beliefs lead to prejudices against these people, making it difficult for them to live fulfilling social lives. With the development of new treatment modalities, such as gene therapy, stem cell therapy, and P-glycoprotein inhibitors, it is more important now than ever to increase the research output for the African region to create the best possible treatment and maximize patient outcomes.
APA Citation
Kassahun Bekele, Bezawit; Nebieridze, Anano; Moses Daniel, Itopa; Byiringiro, Clever; Nazir, Abubakar; Algawork Kibru, Ermias; Wojtara, Magda; and Uwishema, Olivier, "Epilepsy in Africa: a multifaceted perspective on diagnosis, treatment, and community support" (2024). GW Authored Works. Paper 4231.
https://hsrc.himmelfarb.gwu.edu/gwhpubs/4231
Department
Public Health Student Works