Does diet quality matter? A secondary analysis of a randomized clinical trial

Authors

Hana Kahleova, Physicians Committee for Responsible Medicine, Washington, DC, USA. hkahelova@pcrm.org.
Haley Brennan, Physicians Committee for Responsible Medicine, Washington, DC, USA.
Tatiana Znayenko-Miller, Physicians Committee for Responsible Medicine, Washington, DC, USA.
Richard Holubkov, School of Medicine, University of Utah, Salt Lake City, UT, USA.
Neal D. Barnard, Physicians Committee for Responsible Medicine, Washington, DC, USA.

Document Type

Journal Article

Publication Date

11-28-2023

Journal

European journal of clinical nutrition

DOI

10.1038/s41430-023-01371-y

Abstract

This secondary analysis assessed the association of a plant-based index (PDI), healthful (hPDI), and unhealthful (uPDI), with weight loss in overweight adults. Participants (n = 244) were randomly assigned to a vegan (n = 122) or control group (n = 122) for 16 weeks. Three-day dietary records were analyzed and PDI indices were calculated. A repeated measure ANOVA was used for statistical analysis. All three scores increased in the vegan group; the effect sizes were: PDI +10.6 (95% CI +8.6 to +12.6; p < 0.001); hPDI +10.9 (95% CI +8.4 to +13.4; p < 0.001); and uPDI +5.4 (95% CI +3.4 to +7.4; p < 0.001). The change in all three scores significantly correlated with change in body weight: PDI (r = -0.40; p < 0.001); hPDI (r = -0.37; p < 0.001); and uPDI (r = -0.21; p = 0.002). These findings suggest that minimizing the consumption of animal products and oil may be an effective weight loss strategy in overweight adults. ClinicalTrials.gov number, NCT02939638.

APA Citation

Kahleova, Hana; Brennan, Haley; Znayenko-Miller, Tatiana; Holubkov, Richard; and Barnard, Neal D., "Does diet quality matter? A secondary analysis of a randomized clinical trial" (2023). GW Authored Works. Paper 3761.
https://hsrc.himmelfarb.gwu.edu/gwhpubs/3761

Department

Medicine