Assessment and Management of Sleep Disturbances in Atopic Dermatitis: A Review

Authors

Archana Samynathan, From the Department of Dermatology, George Washington University School of Medicine and Health Sciences, Washington, District of Columbia, USA.
Anna B. Fishbein, Department of Allergy and Immunology, Robert and Anne Lurie Children's Hospital, Chicago, Illinois, USA.
Sabra M. Abbott, Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Genery D. Booster, Department of Pediatrics, National Jewish Hospital, Denver, Colorado, USA.
Phyllis C. Zee, Department of Sleep Medicine, Robert and Anne Lurie Children's Hospital, Chicago, Illinois, USA.
Stephen H. Sheldon, Sleep Medicine Center, Ann and Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois, USA.
Gil Yosipovitch, Department of Dermatology, University of Miami Miller School of Medicine, Miami, Florida, USA.
Jonathan I. Silverberg, Department of Dermatology, George Washington University School of Medicine and Health Sciences, Washington, District of Columbia, USA.

Document Type

Journal Article

Publication Date

9-27-2023

Journal

Dermatitis : contact, atopic, occupational, drug

DOI

10.1089/derm.2023.0074

Abstract

Atopic dermatitis (AD) is a chronic burdensome inflammatory skin disease with well-established cutaneous and systemic comorbidities and disease burden. AD particularly has profound impacts on sleep in individuals of all ages. Sleep disturbances (SDs) affect 6.2% of school-age children and 33-87.1% of adults with AD. This narrative review addresses the burden of SD in AD patients, as well as biological mechanisms of SD in AD, including biological clocks influencing sleep, inflammation, and behavior. Approaches for early detection, diagnosis, objective quantification, patient education, and management are reviewed. It is imperative to break the itch-scratch cycle to reduce SDs and improve quality of life in individuals with AD.

APA Citation

Samynathan, Archana; Fishbein, Anna B.; Abbott, Sabra M.; Booster, Genery D.; Zee, Phyllis C.; Sheldon, Stephen H.; Yosipovitch, Gil; and Silverberg, Jonathan I., "Assessment and Management of Sleep Disturbances in Atopic Dermatitis: A Review" (2023). GW Authored Works. Paper 3342.
https://hsrc.himmelfarb.gwu.edu/gwhpubs/3342

Department

Dermatology