Severe reactive infectious mucocutaneous eruption mimicking drug-induced epidermal necrolysis triggered by norovirus

Authors

Eric Sanfilippo, The George Washington University School of Medicine and Health Sciences, Washington, DC, USA.
Kaiane Habeshian, The George Washington University School of Medicine and Health Sciences, Washington, DC, USA.
Colleen H. Cotton, The George Washington University School of Medicine and Health Sciences, Washington, DC, USA.
Anna Yasmine Kirkorian, The George Washington University School of Medicine and Health Sciences, Washington, DC, USA.

Document Type

Journal Article

Publication Date

6-14-2023

Journal

Pediatric dermatology

DOI

10.1111/pde.15370

Keywords

DEN; RIME; SJS; Stevens-Johnson syndrome; TEN; drug-induced epidermal necrolysis; mucositis; norovirus; reactive mucocutaneous eruption; toxic epidermal necrolysis

Abstract

Reactive infectious mucocutaneous eruption (RIME) is an eruptive mucositis with varying degrees of cutaneous involvement presumed to be due to an immunologic response to various infectious pathogens. Most reported cases occur after a prodromal upper respiratory illness. We present a patient with a particularly severe case mimicking drug-induced epidermal necrolysis found to be triggered by asymptomatic norovirus infection, a virus not previously reported in association with RIME.

APA Citation

Sanfilippo, Eric; Habeshian, Kaiane; Cotton, Colleen H.; and Kirkorian, Anna Yasmine, "Severe reactive infectious mucocutaneous eruption mimicking drug-induced epidermal necrolysis triggered by norovirus" (2023). GW Authored Works. Paper 2720.
https://hsrc.himmelfarb.gwu.edu/gwhpubs/2720

Department

Dermatology