Postoperative Complications After Interpolated Flap Repair for Mohs Defects of the Nose: A Multicenter Prospective Cohort Study

Allison M. Perz, Cooper Medical School of Rowan University, Camden, New Jersey.
Tess M. Lukowiak, Drexel University College of Medicine, Philadelphia, Pennsylvania.
Michael P. Lee, Eastern Virginia Medical School, Norfolk, Virginia.
Donald Neal, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania.
Leora Aizman, George Washington University School of Medicine and Health Sciences, Washington, District of Columbia.
Christopher J. Miller, Department of Dermatology, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania.
Nicholas Golda, Department of Dermatology, University of Missouri, Columbia, Missouri.
John G. Albertini, The Skin Cancer Surgery Center, Winston-Salem, North Carolina.
Todd Holmes, Division of Dermatology, University of Vermont Medical Center, Burlington, Vermont.
Anna Bar, Department of Dermatology, Oregon Health & Science University, Portland, Oregon.
Justin Leitenberger, Department of Dermatology, Oregon Health & Science University, Portland, Oregon.
Ian Maher, Department of Dermatology, University of Minnesota, Minneapolis, Minnesota.
Joseph F. Sobanko, Department of Dermatology, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania.
David Chen, Division of Dermatology, University of Vermont Medical Center, Burlington, Vermont.
Tyler Hollmig, Division of Dermatology, University of Texas Dell Medical Center, Austin, Texas.
Sumaira Aasi, Department of Dermatology, Stanford University, Stanford, California.
Adam Sutton, Department of Dermatology, University of Nebraska Medical Center, Omaha, Nebraska.
H William Higgins, Department of Dermatology, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania.
Thuzar M. Shin, Department of Dermatology, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania.
Christine Weinberger, Division of Dermatology, University of Vermont Medical Center, Burlington, Vermont.
Adam Mattox, Department of Dermatology, University of Minnesota, Minneapolis, Minnesota.
Ashley Wysong, Department of Dermatology, University of Nebraska Medical Center, Omaha, Nebraska.
Jeremy R. Etzkorn, Department of Dermatology, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania.

Document Type

Journal Article

Publication Date

2-1-2023

Journal

Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]

Volume

49

Issue

2

DOI

10.1097/DSS.0000000000003653

Abstract

BACKGROUND: Dermatologists perform most interpolated flaps after skin cancer resection. Prospective, multicenter data on complications after interpolated flap repair in this setting are limited. OBJECTIVE: To determine the rate of physician-reported complications after interpolated flap repair of the nose. METHODS: Multicenter, prospective cohort study of 169 patients undergoing 2-stage interpolated flap repair of post-Mohs nasal defects. Frequency of bleeding, infection, dehiscence, necrosis, hospitalization, and death in the 30 days after flap placement and flap takedown are reported. RESULTS: Patients experienced 23 complications after flap placement (13.61%) and 6 complications after flap takedown (3.55%) that were related to the surgical procedure. The most frequent complication after flap placement was bleeding (9, 5.33%, 95% confidence interval [CI]: 2.83%-9.82%). The most frequent complication after flap takedown was infection (5, 2.96%, 95% CI: 1.27%-6.74%). There was one hospitalization related to an adverse reaction to antibiotics. There were no deaths. CONCLUSION: Most complications after interpolated flap repair for post-Mohs defects of the nose are minor and are associated with flap placement. Interpolated flap repair for post-Mohs defects can be performed safely in the outpatient setting under local anesthesia.

Department

School of Medicine and Health Sciences Student Works

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