The Right Ventricle in the Trans-Catheter Era: A Perspective for Planning Interventions

Authors

Jared L. Antevil, Division of Cardiothoracic Surgery and Heart Center, Washington D.C. Veterans Affairs Medical Center, Washington, D.C.. Electronic address: Jared.Antevil@va.gov.
Michael A. Napolitano, Division of Cardiothoracic Surgery and Heart Center, Washington D.C. Veterans Affairs Medical Center, Washington, D.C.; Department of Surgery, George Washington University, Washington, D.C.
Federico E. Mordini, Division of Cardiothoracic Surgery and Heart Center, Washington D.C. Veterans Affairs Medical Center, Washington, D.C.
Patrick M. McCarthy, Department of Surgery, Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Gregory D. Trachiotis, Division of Cardiothoracic Surgery and Heart Center, Washington D.C. Veterans Affairs Medical Center, Washington, D.C.; Department of Surgery, George Washington University, Washington, D.C.

Document Type

Journal Article

Publication Date

1-1-2022

Journal

Seminars in thoracic and cardiovascular surgery

Volume

34

Issue

3

DOI

10.1053/j.semtcvs.2021.07.030

Keywords

Left-sided valve disease; Right ventricle; Transcatheter interventions

Abstract

Dysfunction of the right ventricle (RV) is common in patients with advanced left-sided valve disease and the significant impact of RV dysfunction on both short and long-term outcome is well established. However, considerations of RV function are largely absent in current management guidelines for valve disease and cardiac procedural risk models. As the indications and use of trans-catheter therapies rapidly expand for patients with acquired valvular disease, it is critical for clinicians to understand and consider RV function when making decisions for these patients. This review summarizes contemporary data on the assessment of RV function, the prognostic importance of baseline RV dysfunction on surgical and transcatheter procedures for acquired left-sided valvular disease, and the relative impact of these interventions on RV function. Baseline RV dysfunction is a powerful predictor of poor short- and long-term outcome after any therapeutic intervention for acquired left-sided cardiac valve disease. Surgical intervention for aortic or mitral valve disease is associated with a significant but transient decline in RV function, whereas trans-catheter procedures generally do not appear to have detrimental effects on either longitudinal or global RV function. Guidelines for therapy in patents with acquired left-sided valvular disease should account for RV dysfunction. Whereas surgical intervention in these patients leads to a predictable decline in RV function, trans-catheter therapies largely do not appear to have this effect. Further study is needed to determine the impact of these findings on current practice.

APA Citation

Antevil, Jared L.; Napolitano, Michael A.; Mordini, Federico E.; McCarthy, Patrick M.; and Trachiotis, Gregory D., "The Right Ventricle in the Trans-Catheter Era: A Perspective for Planning Interventions" (2022). GW Authored Works. Paper 1865.
https://hsrc.himmelfarb.gwu.edu/gwhpubs/1865

Department

Surgery