Patient-Reported Nasal Function and Appearance After Interpolation Flap Repair Following Skin Cancer Resection: A Multicenter Prospective Cohort Study

Surya A. Veerabagu, Tulane University School of Medicine, New Orleans, Louisiana, USA.
Allison M. Perz, Cooper Medical School of Rowan University, Camden, New Jersey, USA.
Tess M. Lukowiak, Drexel University College of Medicine, Philadelphia, Pennsylvania, USA.
Michael P. Lee, Eastern Virginia Medical School, Norfolk, Virginia, USA.
Donald Neal, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
Leora Aizman, George Washington University School of Medicine and Health Sciences, Washington, District of Columbia.
Christopher J. Miller, Department of Dermatology, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Nicholas Golda, Department of Dermatology, University of Missouri, Columbia, Missouri, USA.
John G. Albertini, The Skin Surgery Center, Winston-Salem, North Carolina, USA.
David Chen, Division of Dermatology, University of Vermont Medical Center, Burlington, Vermont, USA.
Anna Bar, Department of Dermatology, Oregon Health & Science University, Portland, Oregon, USA.
Justin Leitenberger, Department of Dermatology, Oregon Health & Science University, Portland, Oregon, USA.
Ian A. Maher, Department of Dermatology, University of Minnesota, Minneapolis, Minnesota, USA.
Joseph F. Sobanko, Department of Dermatology, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Tyler Hollmig, Division of Dermatology, University of Texas Dell Medical Center, Austin, Texas, USA.
Sumaira Aasi, Department of Dermatology, Stanford University, Stanford, California, USA.
Adam Sutton, Department of Dermatology, University of Nebraska Medical Center, Omaha, Nebraska, USA.
H William Higgins Ii, Department of Dermatology, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Thuzar M. Shin, Department of Dermatology, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Christine Weinberger, Division of Dermatology, University of Vermont Medical Center, Burlington, Vermont, USA.
Adam Mattox, Department of Dermatology, University of Minnesota, Minneapolis, Minnesota, USA.
Ashley Wysong, Department of Dermatology, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Shannon T. Nugent, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
Jeremy R. Etzkorn, Department of Dermatology, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, USA.

Document Type

Journal Article

Publication Date

8-10-2022

Journal

Facial plastic surgery & aesthetic medicine

DOI

10.1089/fpsam.2021.0271

Abstract

Among patients undergoing two-stage interpolated flap repair of nasal defects, nasal function, and appearance before surgery and at 16 weeks after flap takedown were compared using the Nasal Appearance and Function Evaluation Questionnaire (NAFEQ). Multicenter prospective cohort study. Adult patients with a nasal skin cancer anticipated to require two-stage interpolation flap repair completed the NAFEQ before surgery, at 1 week after flap placement, 4 weeks after flap takedown, and 16 weeks after flap takedown. One hundred sixty-nine patients were enrolled, with 138 patients completing both presurgical and 16-week post-takedown NAFEQs. Overall NAFEQ score increased by 1.09 points (1.91% improvement, confidence interval [95% CI -0.34 to 2.53]). NAFEQ functional subscale increased by 0.72 points (2.58% increase; 95% CI [0.10-1.35]) and appearance subscale increased by 0.37 points (1.28% improvement, 95% CI [-0.65 to 1.39]). At 16 weeks after flap takedown, patients' perceptions of their nasal function and appearance are similar to or slightly improved when compared with their presurgical assessments.

Department

School of Medicine and Health Sciences Student Works

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