Title

Clinical H MRS in childhood neurometabolic diseases-part 1: technique and age-related normal spectra

Document Type

Journal Article

Publication Date

2-18-2022

Journal

Neuroradiology

DOI

10.1007/s00234-022-02917-w

Keywords

MRS; Metabolic; Metabolism; Spectroscopy

Abstract

Despite its vigorous ability to detect and measure metabolic disturbances, H MRS remains underutilized in clinical practice. MRS increases diagnostic yield and provides therapeutic measures. Because many inborn metabolic errors are now treatable, early diagnosis is crucial to prevent or curb permanent brain injury. Therefore, patients with known or suspected inborn metabolic errors stand to benefit from the addition of MRS. With education and practice, all neuroradiologists can perform and interpret MRS notwithstanding their training and prior experience. In this two-part review, we cover the requisite concepts for clinical MRS interpretation including technical considerations and normal brain spectral patterns based on age, location, and methodology.

Department

Pediatrics

Share

COinS