Clinical H MRS in childhood neurometabolic diseases - part 2: MRS signatures

Authors

Matthew T. Whitehead, Department of Neuroradiology, Children's National Hospital, 111 Michigan Ave NW, Washington, DC, 20010, USA. MWhitehe@childrensnational.org.
Lillian M. Lai, Department of Radiology, Children's Hospital of Los Angeles, Los Angeles, CA, USA.
Stefan Blüml, Department of Radiology, Children's Hospital of Los Angeles, Los Angeles, CA, USA.

Document Type

Journal Article

Publication Date

2-28-2022

Journal

Neuroradiology

DOI

10.1007/s00234-022-02918-9

Keywords

MRS; Metabolic; Metabolism; Spectroscopy

Abstract

Proton MRS of the brain provides the ability to gather direct information regarding the metabolic status of the brain at the time of MRI. Although selective vulnerability of brain tissue may yield distinct imaging patterns in neurometabolic disorders, it is not uncommon for the brain MRI to be normal, nonspecific, or show ambiguous abnormalities among several possible diagnoses, metabolic, or otherwise. This review highlights childhood neurometabolic diseases in which H MRS may show diagnostic or suggestive metabolic profiles without complicated acquisition or postprocessing techniques.

APA Citation

Whitehead, Matthew T.; Lai, Lillian M.; and Blüml, Stefan, "Clinical H MRS in childhood neurometabolic diseases - part 2: MRS signatures" (2022). GW Authored Works. Paper 106.
https://hsrc.himmelfarb.gwu.edu/gwhpubs/106

Department

Radiology