Biorepository best practices for research and clinical investigations

Authors

Micheline Sanderson-November, Department of Pathology, University of Stellenbosch, Stellenbosch, Cape Town, South Africa. Electronic address: msanders@sun.ac.za.
Sylvia Silver, Department of Microbiology, Immunology and Tropical Medicine, George Washington University, Washington, District of Columbia, United States of America. Electronic address: ssilver@gwu.edu.
Vanessa Hooker, Department of Pathology, University of Arizona, Tucson, Arizona, United States of America.
Monika Schmelz, Department of Pathology, University of Arizona, Tucson, Arizona, United States of America. Electronic address: schmelz@email.arizona.edu.

Document Type

Journal Article

Publication Date

5-1-2022

Journal

Contemporary clinical trials

Volume

116

DOI

10.1016/j.cct.2021.106572

Abstract

Translational research requires good quality specimens to ensure the integrity of research results. Clinical research must rely not only on quality specimens, but as well on clinical annotation for consistent, accurate and verifiable scientific and clinical outcomes. In laboratory research performed on a specimen by a single investigator, quality control is easily maintained. In a multi-site clinical research network, the numerous steps for biospecimens from procurement through transport, processing, storage and ultimately testing requires strict standardization of operational workflows and procedures. The practices of a central biorepository can inform and contribute to best practices regarding clinical research specimen integrity for multi-site clinical research.

APA Citation

Sanderson-November, Micheline; Silver, Sylvia; Hooker, Vanessa; and Schmelz, Monika, "Biorepository best practices for research and clinical investigations" (2022). GW Authored Works. Paper 1017.
https://hsrc.himmelfarb.gwu.edu/gwhpubs/1017

Department

Microbiology, Immunology, and Tropical Medicine