School of Medicine and Health Sciences Poster Presentations

Poster Number

157

Document Type

Poster

Status

Medical Student

Abstract Category

Clinical Specialties

Keywords

Acute pancreatitis, chronic pancreatitis, gallstone disease, alcohol ingestion

Publication Date

Spring 2018

Abstract

Study Objective: Approximately 30% of patients with one episode of acute pancreatitis experience a recurrent episode. The objective of this study is to compare the severity of the first-time episode versus recurrent episodes of acute pancreatitis based on CT scan.

Methods: This study was conducted as part of a retrospective chart review at a single academic urban emergency department from 2012-2016. Criteria for inclusion included clinical symptoms of pancreatitis, age greater than or equal to 18 years, ED diagnosis of acute pancreatitis, and, an abdominal CT scan within 24 hours of triage. Exclusion criteria were traumatic cause of acute pancreatitis and pregnancy. Charts were reviewed by a trained abstractor using structured data collection sheets which included data elements such as a history of acute pancreatitis and the results of an abdominal CT scan. Data abstraction was confirmed for interrater reliability. CT Scans were graded using the Modified CT Severity Index (MCTSI) which grades acute pancreatitis by the presence of inflammation, fluid accumulation, necrosis or extra-pancreatic findings.

Results: 283 patients were included in the study. Of these, 110 patients resented with recurrent acute pancreatitis and 173 patients presented with first-time acute pancreatitis. We calculated the mean MCTSI score in both groups and found a significantly higher rate of severity in recurrent acute pancreatitis versus first episode (2.09 vs. 1.43, p<0.05.)

Conclusion: Patients with recurrent acute pancreatitis are more likely to present with a more severe episode of acute pancreatitis than patients presenting with first-time acute pancreatitis.

Creative Commons License

Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License.

Open Access

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Comments

Presented at GW Annual Research Days 2018.

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Recurrent Episodes of Acute Pancreatitis Present to the ED with More Severe Disease by CT than First-Time Acute Pancreatitis

Study Objective: Approximately 30% of patients with one episode of acute pancreatitis experience a recurrent episode. The objective of this study is to compare the severity of the first-time episode versus recurrent episodes of acute pancreatitis based on CT scan.

Methods: This study was conducted as part of a retrospective chart review at a single academic urban emergency department from 2012-2016. Criteria for inclusion included clinical symptoms of pancreatitis, age greater than or equal to 18 years, ED diagnosis of acute pancreatitis, and, an abdominal CT scan within 24 hours of triage. Exclusion criteria were traumatic cause of acute pancreatitis and pregnancy. Charts were reviewed by a trained abstractor using structured data collection sheets which included data elements such as a history of acute pancreatitis and the results of an abdominal CT scan. Data abstraction was confirmed for interrater reliability. CT Scans were graded using the Modified CT Severity Index (MCTSI) which grades acute pancreatitis by the presence of inflammation, fluid accumulation, necrosis or extra-pancreatic findings.

Results: 283 patients were included in the study. Of these, 110 patients resented with recurrent acute pancreatitis and 173 patients presented with first-time acute pancreatitis. We calculated the mean MCTSI score in both groups and found a significantly higher rate of severity in recurrent acute pancreatitis versus first episode (2.09 vs. 1.43, p<0.05.)

Conclusion: Patients with recurrent acute pancreatitis are more likely to present with a more severe episode of acute pancreatitis than patients presenting with first-time acute pancreatitis.

 

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