Journal of Aging Research
Article ID 803864
We examined the relation between stress reactivity and 24 h glycemic control in 17 inactive, healthy older people (≥60 years) under both a novel psychophysical stress and a seated control condition. Plasma cortisol was measured over the course of the stress and recovery periods. Glycemic control was determined over the subsequent 3 h from an oral glucose tolerance test (OGTT) and over 24 h viacontinuous glucose monitoring (CGM). We observed significant (� < 0 . 0 5) elevations in perceived stress, cardiovascular activity, and peak cortisol response at 30 min (1 0 . 6 ± 3 . 1 versus 8 . 6 ± 2 . 6 μg·dL−1, resp.) during the stress compared with the control condition; however, 3 h OGTT glucose and insulin responses were similar between conditions. The CGM data suggested a 30–40 min postchallenge delay in peak glucose response and attenuated glucose clearance over the 6 h following the stress condition, but these alterations were not statistically significant. Healthy older people may demonstrate minimal disruption in metabolic resiliency following everyday psychological stress.
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DiPietro, L., Yeckel, C.W., Gribok, A. (2012). Response to acute psychophysical stress and 24-hour glycemic control in healthy older people. Journal of Aging Research:803864.