c-ANCA Positive Necrotizing Crescentic Glomerulonephritis with Linear Immunoglobulin Staining

Authors

Akshita Mehta, George Washington UniversityFollow

Document Type

Poster

Keywords

c-ANCA; Glomerulonephritis

Publication Date

Spring 4-1-2015

Abstract

Necrotizing crescentic glomerulonephritis is found in anti-glomerular basement membrane (GBM) disease (Type 1), immune complex (Type 2) deposition and anti-neutrophil cytoplasmic (ANCA)-related disease (Type 3).

ANCA positive glomerulonephritis is typically characterized on renal biopsy as pauci-immune, with mild or absent glomerular staining for immunoglobulin, or complement staining by immunofluorescence.

Rare cases of concomitant p-ANCA plus linear immunofluorescence pattern staining have been discussed, however none with prior association with c-ANCA.

We report a case of systemic c-ANCA pulmonary-renal syndrome with anti-GBM-disease-typical linear staining on renal biopsy immunofluorescence.

Open Access

1

Comments

Presented at: GW Research Days 2015.