Journal of Law, Medicine and Ethics
Volume 36, Issue 3
Anticonvulsants--adverse effects; Asian Continental Ancestry--genetics; Carbamazepine--adverse effects; HLA-B Antigents--genetics; Pharmacogenetics; Genetics
The article discusses various aspects of ancestry-based drug prescribing and contemporary medical ethics in the U.S. Ancestry has been used by researchers to identify a subgroup of people most likely to have a certain allele linked to an adverse drug response. Also discussed are carbamazepine labeling, the U.S. Food and Drug Administration's (FDA) Alert on drug prescribing based on allele testing and the ethics of genetically categorizing people.
Payne, P.W. (2008). For Asians only? The perils of ancestry-based drug prescribing. Journal of Law, Medicine, and Ethics, 36(3), 585-588.