Treatment of akinetic mutism with intramuscular olanzapine: A case series

Authors

David R. Spiegel, Eastern Virginia Medical School
Daniel P. Casella, Eastern Virginia Medical School
David M. Callender, Eastern Virginia Medical School
Neetu Dhadwal, Eastern Virginia Medical School

Document Type

Journal Article

Publication Date

1-1-2008

Journal

Journal of Neuropsychiatry and Clinical Neurosciences

Volume

20

Issue

1

DOI

10.1176/jnp.2008.20.1.93

Abstract

Akinetic mutism is a wakeful state of severe apathy and paucity of volitional movement. Evidence indicates a possible dopaminergic hypofunction within the anterior cingulate cortex. The authors present three cases of acute onset akinetic mutism successfully treated with intramuscular olanzapine. Copyright © 2008 American Psychiatric Publishing, Inc.

APA Citation

Spiegel, D., Casella, D., Callender, D., & Dhadwal, N. (2008). Treatment of akinetic mutism with intramuscular olanzapine: A case series. Journal of Neuropsychiatry and Clinical Neurosciences, 20 (1). http://dx.doi.org/10.1176/jnp.2008.20.1.93