Title

Alcohol, stem cells and cancer

Document Type

Journal Article

Publication Date

9-1-2017

Journal

Genes and Cancer

Volume

8

Issue

9-10

DOI

10.18632/genesandcancer.156

Keywords

Alcohol; Cancer; DNA repair; Stem cells; TGF-β

Abstract

© Gu et al. Dosage, gender, and genetic susceptibility to the effects of alcohol remained only partially elucidated. In this review, we summarize the current knowledge of the mechanisms underlying the role of alcohol in liver and gastrointestinal cancers. In addition, two recent pathways- DNA repair and TGF-β signaling which provide new insights into alcohol in the regulation of cancers and stem cells are also discussed here.

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