Alcohol, stem cells and cancer

Authors

Shoujun Gu, The George Washington University
Bao Ngoc Nguyen, The George Washington University
Shuyun Rao, The George Washington University
Shulin Li, University of Texas MD Anderson Cancer Center
Kirti Shetty, Johns Hopkins School of Medicine
Asif Rashid, University of Texas MD Anderson Cancer Center
Vivek Shukla, National Cancer Institute (NCI)
Chu Xia Deng, The George Washington University
Lopa Mishra, The George Washington University
Bibhuti Mishra, The George Washington University

Document Type

Journal Article

Publication Date

9-1-2017

Journal

Genes and Cancer

Volume

8

Issue

9-10

DOI

10.18632/genesandcancer.156

Keywords

Alcohol; Cancer; DNA repair; Stem cells; TGF-β

Abstract

© Gu et al. Dosage, gender, and genetic susceptibility to the effects of alcohol remained only partially elucidated. In this review, we summarize the current knowledge of the mechanisms underlying the role of alcohol in liver and gastrointestinal cancers. In addition, two recent pathways- DNA repair and TGF-β signaling which provide new insights into alcohol in the regulation of cancers and stem cells are also discussed here.

APA Citation

Gu, S., Nguyen, B., Rao, S., Li, S., Shetty, K., Rashid, A., Shukla, V., Deng, C., Mishra, L., & Mishra, B. (2017). Alcohol, stem cells and cancer. Genes and Cancer, 8 (9-10). http://dx.doi.org/10.18632/genesandcancer.156