Celiac disease and diabetes mellitus diagnosed in a pediatric patient with hirschsprung disease
Fetal and Pediatric Pathology
Aganglionosis; Autoimmune enteropathy; Celiac disease; Diabetes mellitus; Hirschsprung disease; Human leukocyte antigen; Neurocristopathies
Hirschsprung disease is a disorder of neural crest migration characterized by intestinal aganglionosis along a variable segment of the gastrointestinal tract. It is a complex disorder associated with several syndromes. Celiac disease is an autoimmune enteropathy characterized by dietary intolerance to gluten proteins and can be associated with autoimmune conditions such as diabetes mellitus. Celiac disease can mimic Hirschsprung disease when presenting with constipation and abdominal distention. We present the case of celiac disease diagnosed in a patient with Hirschsprung disease who subsequently developed type one diabetes mellitus. Copyright © Informa Healthcare USA, Inc.
Menchise, A., Condino, A., Levitt, M., Hebra, A., & Wilsey, M. (2013). Celiac disease and diabetes mellitus diagnosed in a pediatric patient with hirschsprung disease. Fetal and Pediatric Pathology, 32 (1). http://dx.doi.org/10.3109/15513815.2012.659396