Title

Vancomycin Prevents Polytetrafluoroethylene Graft Infections in Pediatric Patients Receiving Chronic Hemodialysis

Document Type

Journal Article

Publication Date

1-1-1985

Journal

American Journal of Kidney Diseases

Volume

5

Issue

2

DOI

10.1016/S0272-6386(85)80007-X

Keywords

Hemodialysis; PTFE grafts; vancomycin

Abstract

Polytetrafluoroethylene (PTFE) grafts have been a useful addition to the pediatric hemodialysis vascular access armamentarium. In this study, 17 pediatric patients underwent 331 total months of hemodialysis via PTFE grafts. There was a statistically significant (P < .025) decrease in the incidence of graft infections in 12 patients (235 patient-months) while receiving prophylactic parenteral vancomycin compared with 9 patients (96 patient-months) while receiving no vancomycin (0% v 44%). Vancomycin side effects were uncommon and mild. Vancomycin is a safe and effective agent for the prevention of PTFE graft infections in pediatric patients receiving chronic hemodialysis. © 1985, National Kidney Foundation Inc.. All rights reserved.

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