Title

Smooth Muscle Conditions of the Chest: A Clinical, Radiologic, and Pathologic Review

Document Type

Journal Article

Publication Date

1-1-2020

Journal

Journal of Thoracic Imaging

DOI

10.1097/RTI.0000000000000567

Keywords

immunohistochemistry; leiomyoma; leiomyosarcoma; lymphangioleiomyomatosis; smooth muscle tumor

Abstract

Smooth muscle conditions of the chest have diverse clinical and imaging manifestations and may involve nearly every thoracic structure. Differentiation among these conditions requires the integration of clinical, radiologic, and histopathologic data. Histologic examination in conjunction with immunohistochemistry is essential for differentiation from other spindle cell neoplastic mimics. Familiarity with these entities will ensure the inclusion of smooth muscle conditions in the differential diagnosis of thoracic soft tissue lesions and potentially guide the clinician in appropriate management. We review the clinical, imaging, and histopathologic features of thoracic smooth muscle-related conditions organized by the anatomic structures affected.

Share

COinS