Title

Anger experiences among hepatitis C patients: Relationship to depressive symptoms and health-related quality of life

Document Type

Journal Article

Publication Date

1-1-2007

Journal

Psychosomatics

Volume

48

Issue

3

DOI

10.1176/appi.psy.48.3.223

Abstract

The authors examined anger among hepatitis C (HCV) patients and its relationship to health-related quality of life (HRQL) and depression. Eighty-seven HCV patients who received pegylated interferon-alpha2b and ribavirin were included. Patients' mean age was 48 years; 42% were women, and 60% were white. Patients experienced moderate anger while undergoing HCV treatment. Angry feelings increased during treatment in some domains, specifically, Control Over Anger and Angry Reaction. Greater anger was associated with more depression and poorer HRQL. Findings point to the importance for physicians to screen for a wide range of neuropsychiatric side effects of interferon, including anger. © 2007 The Academy of Psychosomatic Medicine.

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