Title

Choline acetyltransferase-immunoreactive neurons in fetal monkey cerebral cortex

Document Type

Journal Article

Publication Date

12-15-1987

Journal

Developmental Brain Research

Volume

37

Issue

1-2

DOI

10.1016/0165-3806(87)90252-5

Keywords

Acetylcholine; Cerebral cortex; Immunocytochemistry; Non-pyramidal neuron

Abstract

Two monoclonal antibodies to choline acetyltransferase (ChAT) were used to stain the cerebral cortex of fetal monkeys at 110-150 days post-conception. In addition to a small number of immunostained fibers, cells resembling typical non-pyramidal neurons were immunostained in developing layers V and VI and in the subjacent white matter of each area examined (sensory-motor and visual areas). ChAT-immunoreactive neurons have not been described in the cerebral cortex of adult primates, but the present observations indicate such neurons exist in the developing primate cortex. © 1987.

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