Ovotestis in Adolescence: 2 Case Reports

Authors

Jyoti D. Chouhan, SUNY Downstate Health Sciences University
David I. Chu, The Children's Hospital of Philadelphia
Antoinette Birs, UCF College of Medicine
Louise C. Pyle, The Children's Hospital of Philadelphia
Jason P. Van Batavia, The Children's Hospital of Philadelphia
Rebecca L. Linn, The Children's Hospital of Philadelphia
Susan J. Back, The Children's Hospital of Philadelphia
Pierre Russo, The Children's Hospital of Philadelphia
Kassa Darge, The Children's Hospital of Philadelphia
Thomas F. Kolon, The Children's Hospital of Philadelphia
Arun K. Srinivasan, The Children's Hospital of Philadelphia

Document Type

Journal Article

Publication Date

7-1-2017

Journal

Urology

Volume

105

DOI

10.1016/j.urology.2017.04.009

Abstract

We present 2 patients found to have ovotesticular disorder of sexual development (otDSD) in late adolescence. Two 15-year-old phenotypically male patients presented to a large pediatric hospital with different complaints: 1 with concern for testicular rupture after a straddle injury; 1 with gynecomastia. Further workup, including imaging and laboratory tests, was performed before surgical exploration. The first patient had unilateral ovotestis, contralateral testis, and SRY-negative 46,XX karyotype. The second patient with gynecomastia had unilateral ovotestis with hemi-uterus and fallopian tube, contralateral ovarian tissue, and 46,XX/47,XXY Klinefelter mosaic karyotype. Although rare, phenotypically normal male patients may present later with ovotesticular disorder of sexual development.

APA Citation

Chouhan, J., Chu, D., Birs, A., Pyle, L., Van Batavia, J., Linn, R., Back, S., Russo, P., Darge, K., Kolon, T., & Srinivasan, A. (2017). Ovotestis in Adolescence: 2 Case Reports. Urology, 105 (). http://dx.doi.org/10.1016/j.urology.2017.04.009