Title

NEDD4-family E3 ligase dysfunction due to PKHD1/Pkhd1 defects suggests a mechanistic model for ARPKD pathobiology.

Document Type

Journal Article

Publication Date

8-10-2017

Journal

Scientific Reports

Volume

7

Issue

1

DOI

10.1038/s41598-017-08284-4

Keywords

Animals; Biomarkers; Cell Line; Disease Models, Animal; Enzyme Activation; Gene Expression; Humans; Intracellular Space; Male; Mice; Mice, Knockout; Mice, Transgenic; Models, Biological; Mutation; Nedd4 Ubiquitin Protein Ligases; Polycystic Kidney, Autosomal Recessive; Protein Transport; Rats; Receptors, Cell Surface; Signal Transduction; rho GTP-Binding Proteins

Peer Reviewed

1

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