Title

New Approaches and Trials in Pediatric Transfusion Medicine

Document Type

Journal Article

Publication Date

6-1-2019

Journal

Hematology/Oncology Clinics of North America

Volume

33

Issue

3

DOI

10.1016/j.hoc.2019.01.012

Keywords

Blood substitutes; Hemoglobin-based oxygen carriers; Pathogen reduction technology; Pediatric transfusion practice; Platelet additive solutions

Abstract

© 2019 Elsevier Inc. Blood transfusions are frequently lifesaving, but there is growing awareness of their associated infectious and noninfectious adverse events. Patient blood management advocates for judicious use of transfusions and considerations of alternatives to correct anemia or achieve hemostasis. Several transfusion practices, either already implemented or under investigation, aim to further improve the safety of transfusions. An enduring challenge in pediatric and neonatal transfusion practice is that studies typically focus on adults, and findings are extrapolated to younger patients. This article aims to summarize some of the newer developments in transfusion medicine with a focus on the neonatal and pediatric population.

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