Indolent CD8-positive T-cell lymphoid proliferation of the ear: A report of two cases
Journal of Cutaneous Pathology
CD8-positive; CTCL; ear; indolent; lymphoma
The current classification of primary cutaneous T-cell lymphoma (CTCL) of the World Health Organization (WHO) includes primary cutaneous CD8-positive aggressive epidermotropic cytotoxic T-cell lymphoma as a provisional entity awaiting cumulative data. Recent reports identify CD3/CD8-positive clonal T-cell lymphoid proliferations arising in the ear and nose that behave indolently and therefore defy currently established subclassification. Here, we report two cases of clonal CD8-positive/granzyme-B-negative T-cell lymphoid proliferations that arose in the ear and behaved indolently. Collectively, these cases suggest that an additional category of cutaneous indolent CD8-positive T-cell lymphoma may be necessary among the existing classification schemes. Zeng W, Nava VE, Cohen P, Ozdemirli M. Indolent CD8-positive T-cell lymphoid proliferation of the ear: a report of two cases. Copyright © 2012 John Wiley & Sons A/S.
Zeng, W., Nava, V., Cohen, P., & Ozdemirli, M. (2012). Indolent CD8-positive T-cell lymphoid proliferation of the ear: A report of two cases. Journal of Cutaneous Pathology, 39 (7). http://dx.doi.org/10.1111/j.1600-0560.2012.01917.x