Title

Solitary fibrous tumor of the kidney - a report of two cases with review of literature

Document Type

Journal Article

Publication Date

8-1-2010

Journal

Korean Journal of Pathology

Volume

44

Issue

4

DOI

10.4132/KoreanJPathol.2010.44.4.420

Keywords

Immunohistochemistry; Kidney; Solitary fibrous tumor

Abstract

Solitary fibrous tumor (SFT) is a benign mesenchymal neoplasm usually occurring in the pleura. Kidney is one of the rarest sites for SFT. We report here on two cases of renal SFT found in 30-year-old and 33-year-old men with review of the literatures. Both cases manifested as well-enhanced solid masses in kidney and radical nephrectomies were done. The tumors consisted of bland-looking spindle cells arranged in short, ill-defined fascicles and storiform pattern with characteristic hemangiopericytoma-like blood vessels. The tumor cells were strongly positive for CD34 and CD99, focally positive for bcl-2, and negative for cytokeratin and human melanoma black-45 on immunohistochemical stainings. Possibility of SFT should be considered in the differential diagnosis of a renal mass which consists of benign-looking spindle cells and hemangiopericytomatous blood vessels. Immunohistochemical staining for CD34 is essential to confirm the renal solitary fibrous tumor. © 2010. Korean Association of Medical Journal Editors.

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