A large advanced seminoma in an older woman with androgen insensitivity syndrome

Authors

Hyun Ok Kim, University of Ulsan, College of Medicine
Chung Hoon Kim, University of Ulsan, College of Medicine
Sun A. Kim, University of Ulsan, College of Medicine
Rae Mi You, University of Ulsan, College of Medicine
Hyuk Jae Kang, University of Ulsan, College of Medicine
Sung Hoon Kim, University of Ulsan, College of Medicine
Hee Dong Chae, University of Ulsan, College of Medicine
Byung Moon Kang, University of Ulsan, College of Medicine

Document Type

Journal Article

Publication Date

6-1-2011

Journal

Clinical and Experimental Reproductive Medicine

Volume

38

Issue

2

DOI

10.5653/cerm.2011.38.2.115

Keywords

Androgen insensitivity syndrome; Gonadectomy; Seminoma

Abstract

A 58-year-old woman who presented with inguinal hernia for the first time was diagnosed as seminoma and complete androgen insensitivity syndrome (CAIS). The patient received a late diagnosis, and therefore she could not take a proper management. CAIS is a rare X-linked recessive disease with an XY karyotype that is caused by androgen receptor defects. It usually present with primary amenorrhea or inguinal hernia. The risk of malignant transformation of undescended testis increases with age, thus gonadectomy should be performed after puberty. We present a case of large advanced seminoma in a woman with CAIS who was neglected and diagnosed lately. © 2011. THE KOREAN SOCIETY FOR REPRODUCTIVE MEDICINE.

APA Citation

Kim, H., Kim, C., Kim, S., You, R., Kang, H., Kim, S., Chae, H., & Kang, B. (2011). A large advanced seminoma in an older woman with androgen insensitivity syndrome. Clinical and Experimental Reproductive Medicine, 38 (2). http://dx.doi.org/10.5653/cerm.2011.38.2.115