Testing of a 3D printed, nanostructured osteochondral implant for knee repair in a small animal model
Advanced Materials - TechConnect Briefs 2017
3D printing; Nanomaterial; Orthopedics; Stem cells
Osteochondral lesions of the knee are difficult injuries to treat [1, 2]. Despite improvements in the diagnosis of these lesions, optimal treatment remains elusive, likely as a result of the complex interactions between host factors and lesions specific factors. Lesions with disrupted cartilage that are unstable are especially difficult to treat in younger and more active patients, with current treatment methods leading to mixed results overtime . New and novel materials used to treat joint injury in these populations need to be compatible with industrial scale quality and economies of scale in order to serve as commercially viable implantable devices. We investigated the feasibility of using three-dimensional biologically inspired implants, manufactured using novel 3-dimensional printing techniques and synthetic bio-nanomaterials for treatment of osteochondral defects in a rodent model.
Holmes, B., Kuo, C., Arumugasaamy, N., Gandhi, N., Rossi, C., Fisher, J., Zhang, L., & Oetgen, M. (2017). Testing of a 3D printed, nanostructured osteochondral implant for knee repair in a small animal model. Advanced Materials - TechConnect Briefs 2017, 3 (). Retrieved from https://hsrc.himmelfarb.gwu.edu/smhs_orthosurg_facpubs/399