Title

Osteochondral lesions of the talus: Current treatment modalities and future possibilities

Document Type

Journal Article

Publication Date

4-1-2006

Journal

Current Opinion in Orthopaedics

Volume

17

Issue

2

DOI

10.1097/01.bco.0000192893.19886.b2

Keywords

Ankle; Biologic; Cartilage; Mesenchymal stem cell; OCT; Osteochondral defect; Scaffold; Talus; Treatment

Abstract

Purpose of review: Symptomatic osteochondral lesions of the talus are a common clinical finding for orthopaedic surgeons that treat disorders of the ankle. Multiple treatment options exist for this entity. We will review recent advances in the understanding of osteochondral defects, their diagnosis and classification, treatment options, and the future direction that the field will take. Recent findings: In the last decade, major clinical progress has been made in the areas of mosaicplasty/osteochondral autograft transplantation, allograft transplantation, and autologous chondrocyte implantation. From the basic science aspect, biologic scaffold and mesenchymal stem cell research are poised to revolutionize the treatment possibilities. Summary: In short, we are on the cusp of a new era in orthopaedic surgery that will bring tissue engineering to the forefront of medicine. In no clinical disorder is this potential more exciting than for the treatment of osteochondral lesions. © 2006 Lippincott Williams & Wilkins.

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