Surface Acoustic Wave devices for ocular drug delivery
Proceedings - IEEE Ultrasonics Symposium
In this work we are reporting on the development of a novel SurfaceAcoustic Wave (SAW) device based on MEMS technology for drug delivery in thetreatment of ocular diseases. The miniaturized SAW drug delivery device will beplaced on the eye surface to allow non-invasive long-term drug application basedon the programmed timeline and electronic control of a drug regiment. Thisnovel drug delivery method is expected to lead to better clinical outcomes inthe treatment of various eye diseases, and improved patient compliance withtherapy. The device can be programmed for delivery of precise amounts of drugsat predetermined times over several months, and will use acoustic streaming topush the drug outside of the reservoir. Our modeling results were obtained usingCOMSOL multiphysics program and Coventor microfluidic simulator. Differentforce values were applied to investigate the force necessary to push the drugthrough the outlet. © 2010 IEEE.
Ghahremani, M., Nabili, M., Mahesh, S., Liu, J., Belyea, D., Geist, C., Zderic, V., & Zaghloul, M. (2010). Surface Acoustic Wave devices for ocular drug delivery. Proceedings - IEEE Ultrasonics Symposium, (). http://dx.doi.org/10.1109/ULTSYM.2010.5935970