Precision medicine in myasthenia graves: begin from the data precision.
Annals of Translational Medicine
Myasthenia gravis (MG) is a prototypic autoimmune disease with overt clinical and immunological heterogeneity. The data of MG is far from individually precise now, partially due to the rarity and heterogeneity of this disease. In this review, we provide the basic insights of MG data precision, including onset age, presenting symptoms, generalization, thymus status, pathogenic autoantibodies, muscle involvement, severity and response to treatment based on references and our previous studies. Subgroups and quantitative traits of MG are discussed in the sense of data precision. The role of disease registries and scientific bases of precise analysis are also discussed to ensure better collection and analysis of MG data.
Li, H., Hong, Y., Xie, Y., Hao, H., & Sun, R. (2016). Precision medicine in myasthenia graves: begin from the data precision.. Annals of Translational Medicine, 4 (6). http://dx.doi.org/10.21037/atm.2016.02.16