Document Type
Journal Article
Publication Date
8-2015
Journal
Journal of Hematology and Thromboembolic Diseases
Volume
3
Inclusive Pages
4
DOI
10.4172/2329-8790.1000215
Abstract
Mantle Cell Lymphoma is a rare B-cell malignancy that can invade almost any structure in the body and recur after short-lived clinical responses. The pathogenesis and clinical features are well defined, but management has not yet been optimized. Induction with traditional immune-chemotherapy regimens that are used in other nonHodgkin lymphomas rarely generate durable remissions. Therefore, clinical research is needed to improve treatment of de novo disease and to establish safe and effective regimens for maintenance and salvage options for relapsed or refractory disease. This comprehensive review discusses disease pathogenesis and focuses on emerging treatment paradigms using novel targeted therapies.
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.
APA Citation
Pant, M.K., Alshenawy, W., Alrajjal, A., Alrohbeh, H., Tabbara, I.A. (2015). Mantle Cell Lymphoma: Current Concepts. Journal of Hematology and Thromboembolic Diseases, 3:4.
Peer Reviewed
1
Open Access
1
Comments
Reproduced with permission of Bentham Science Publishers. Journal of Hematology and Thromboembolic Diseases.