Cocaine promotes both initiation and elongation phase of HIV-1 transcription by activating NF-κB and MSK1 and inducing selective epigenetic modifications at HIV-1 LTR.

Document Type

Journal Article

Publication Date

5-13-2015

Journal

Virology

Volume

483

Inclusive Pages

185-202

DOI

10.1016/j.virol.2015.03.036

Keywords

Cocaine--metabolism; Epigenesis, Genetic--drug effects; HIV-1--drug effects; NF-kappa B--metabolism; Ribosomal Protein S6 Kinases, 90-kDa--metabolism; Transcription, Genetic--drug effects

Peer Reviewed

1

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