Title

Rare coding variants in 35 genes associate with circulating lipid levels-A multi-ancestry analysis of 170,000 exomes.

Authors

George Hindy
Peter Dornbos
Mark D Chaffin
Dajiang J Liu
Minxian Wang
Margaret Sunitha Selvaraj
David Zhang
Joseph Park
Carlos A Aguilar-Salinas
Lucinda Antonacci-Fulton
Diego Ardissino
Donna K Arnett
Stella Aslibekyan
Gil Atzmon
Christie M Ballantyne
Francisco Barajas-Olmos
Nir Barzilai
Lewis C Becker
Lawrence F Bielak
Joshua C Bis
John Blangero
Eric Boerwinkle
Lori L Bonnycastle
Erwin Bottinger
Donald W Bowden
Matthew J Bown
Jennifer A Brody
Jai G Broome
Noël P Burtt
Brian E Cade
Federico Centeno-Cruz
Edmund Chan
Yi-Cheng Chang
Yii-Der I Chen
Ching-Yu Cheng
Won Jung Choi
Rajiv Chowdhury
Cecilia Contreras-Cubas
Emilio J Córdova
Adolfo Correa
L Adrienne Cupples
Joanne E Curran
John Danesh
Paul S de Vries
Ralph A DeFronzo
Harsha Doddapaneni
Ravindranath Duggirala
Susan K Dutcher
Patrick T Ellinor
Leslie S Emery
Jose C Florez
Myriam Fornage
Barry I Freedman
Valentin Fuster
Ma Eugenia Garay-Sevilla
Humberto García-Ortiz
Soren Germer
Richard A Gibbs
Christian Gieger
Benjamin Glaser
Clicerio Gonzalez
Maria Elena Gonzalez-Villalpando
Mariaelisa Graff
Sarah E Graham
Niels Grarup
Leif C Groop
Xiuqing Guo
Namrata Gupta
Sohee Han
Craig L Hanis
Torben Hansen
Jiang He
Nancy L Heard-Costa
Yi-Jen Hung
Mi Yeong Hwang
Marguerite R Irvin
Sergio Islas-Andrade
Gail P Jarvik
Hyun Min Kang
Sharon L R Kardia
Tanika Kelly
Eimear E Kenny
Alyna T Khan
Bong-Jo Kim
Ryan W Kim
Young Jin Kim
Heikki A Koistinen
Charles Kooperberg
Johanna Kuusisto
Soo Heon Kwak
Markku Laakso
Leslie A Lange
Jiwon Lee
Juyoung Lee
Seonwook Lee
Donna M Lehman
Rozenn N Lemaitre
Allan Linneberg
Jianjun Liu
Ruth J F Loos
Steven A Lubitz
Valeriya Lyssenko
Ronald C W Ma
Lisa Warsinger Martin, George Washington University
Angélica Martínez-Hernández
Rasika A Mathias
Stephen T McGarvey
Ruth McPherson
James B Meigs
Thomas Meitinger
Olle Melander
Elvia Mendoza-Caamal
Ginger A Metcalf
Xuenan Mi
Karen L Mohlke
May E Montasser
Jee-Young Moon
Hortensia Moreno-Macías
Alanna C Morrison
Donna M Muzny
Sarah C Nelson
Peter M Nilsson
Jeffrey R O'Connell
Marju Orho-Melander
Lorena Orozco
Colin N A Palmer
Nicholette D Palmer
Cheol Joo Park
Kyong Soo Park
Oluf Pedersen
Juan M Peralta
Patricia A Peyser
Wendy S Post
Michael Preuss
Bruce M Psaty
Qibin Qi
D C Rao
Susan Redline
Alexander P Reiner
Cristina Revilla-Monsalve
Stephen S Rich
Nilesh Samani
Heribert Schunkert
Claudia Schurmann
Daekwan Seo
Jeong-Sun Seo
Xueling Sim
Rob Sladek
Kerrin S Small
Wing Yee So
Adrienne M Stilp
E Shyong Tai
Claudia H T Tam
Kent D Taylor
Yik Ying Teo
Farook Thameem
Brian Tomlinson
Michael Y Tsai
Tiinamaija Tuomi
Jaakko Tuomilehto
Teresa Tusié-Luna
Miriam S Udler
Rob M van Dam
Ramachandran S Vasan
Karine A Viaud Martinez
Fei Fei Wang
Xuzhi Wang
Hugh Watkins
Daniel E Weeks
James G Wilson
Daniel R Witte
Tien-Yin Wong
Lisa R Yanek
Sekar Kathiresan
Daniel J Rader
Jerome I Rotter
Michael Boehnke
Mark I McCarthy
Cristen J Willer
Pradeep Natarajan
Jason A Flannick
Amit V Khera
Gina M Peloso

Document Type

Journal Article

Publication Date

1-6-2022

Journal

American Journal of Human Genetics

Volume

109

Issue

1

Inclusive Pages

81-96

DOI

10.1016/j.ajhg.2021.11.021

Keywords

Alleles; Blood Glucose; Case-Control Studies; Computational Biology; Databases, Genetic; Diabetes Mellitus, Type 2; Exome; Genetic Predisposition to Disease; Genetic Variation; Genetics, Population; Genome-Wide Association Study; Humans; Lipid Metabolism; Lipids; Liver; Molecular Sequence Annotation; Multifactorial Inheritance; Open Reading Frames; Phenotype; Polymorphism, Single Nucleotide

Comments

Epub 2021 Dec 20

Peer Reviewed

1

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