Markers of endothelial dysfunction in men with type 2 diabetes and their clinical significance
Medical News of North Caucasus
Endothelial dysfunction; Endothelium dependent vasodilation; Type 2 diabetes mellitus
We examined 115 men (mean age 54,2±6,2 ys) with type 2 diabetes. The endothelial dysfunction was assessed using biochemical markers (VCAM-1, P-selectin and E-selectin) and doppler ultrasound of the brachial artery. To evaluate the severity of symptoms of diabetes mellitus was used the DSC questionnaire. The study revealed a close relationship between VCAM-1 level and biochemical parameters of lipid metabolism. The level of P-selectin was more influenced on the neurological symptoms of diabetes, as well as parameters of endothelium dependent vasodilatation of blood vessels. E-selectin was correlated with the severity of the diabetic symptoms.
Khripun, I., Dzantieva, E., Vorobyev, S., Gusova, Z., Morgunov, M., Belousov, I., & Kogan, M. (2016). Markers of endothelial dysfunction in men with type 2 diabetes and their clinical significance. Medical News of North Caucasus, 11 (3). http://dx.doi.org/10.14300/mnnc.2016.11108