Title

Is there a relationship between insulin resistance , erectile dysfunction and the level of serum total testosterone in men with type 2 diabetes mellitus

Document Type

Journal Article

Publication Date

1-1-2016

Journal

Medical News of North Caucasus

Volume

11

Issue

4

DOI

10.14300/mnnc.2016.11140

Keywords

Diabetes mellitus; Erectile; Insulin resistance; Testosterone

Abstract

The aim of the study was to evaluate the influence of serum total testosterone (T) on the insulin resistance (IR) and erectile dysfunction in men with type 2 diabetes mellitus (T2DM). Objects were 131 male aged 40-65 years with T2DM. Symptoms of erectile dysfunction and androgen deficiency were assessed by IIEF-5 and AMS questionnaires, IR - by HOMA index. Patients were divided into four groups depending on the level of total T. Weight, body mass index and waist circumference were significantly increased in patients with a decreased level of T. The severity of IR negatively correlated with the T levels. Severity of the symptoms of androgen deficiency and erectile dysfunction increases with the decrease in T levels accompanied by worsening of IR in men with T2DM.

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