Macrolide and clindamycin resistance in Staphylococcus aureus isolates and antibiotic use in a veterans affairs medical center
Infection Control and Hospital Epidemiology
Presented in part: 46th Interscience Conference on Antimicrobial Agents and Chemotherapy; San Francisco, CA; September 27-30, 2006 (Abstract C2-1140). A retrospective analysis of 13,946 Staphylococcus aureus isolates revealed a stable incidence of isolates that were resistant to both clindamycin and erythromycin, but a significantly increasing incidence of isolates that were susceptible to clindamycin and resistant to erythromycin during 1991-1995, 1996-2000, and 2001-2005. The use of macrolides and clindamycin also increased during 1996-2005. The incidence of S. aureus isolates with inducible clindamycin resistance increased steadily and significantly during the period from August 2004 through December 2005. © 2007 by The Society for Healthcare Epidemiology of America. All rights reserved.
Modak, R., Ross, D., & Kan, V. (2008). Macrolide and clindamycin resistance in Staphylococcus aureus isolates and antibiotic use in a veterans affairs medical center. Infection Control and Hospital Epidemiology, 29 (2). http://dx.doi.org/10.1086/526448